Rabbit SirT1 (Ab-47) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRabbit SirT1 (Ab-47)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionSpecificity: SirT1 (Ab-47) detects endogenous levels of total SirT1. This gene encodes a member of the sirtuin family ofproteins, homologs to the yeast Sir2 protein. Members of thesirtuin family are characterized by a sirtuin core domain andgrouped into four classes. The functions of human sirtuinshave not yet been determined; however, yeast sirtuinproteins are known to regulate epigenetic gene silencingand suppress recombination of rDNA.
ImmunogenImmunogen: A synthesized peptide derived from human SirT1.. Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mMNaCl, 0.02% sodium azide and 50% glycerol.. Subcellular location: Cytoplasm. Mitochondrion and Nucleus, PML body.Cytoplasm. Nucleus. Recruited to the nuclear bodies via itsinteraction with PML (PubMed:12006491). Colocalized withAPEX1 in the nucleus (PubMed:19934257). May be found innucleolus, nuclear euchromatin, heterochromatin and innermembrane (PubMed:15469825).
Other Names[NAD-dependent protein deacetylase sirtuin-1 isoform b; NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; hSIR2; hSIRT1; SIR2alpha; sir2-like 1; sirtuin type 1; SIR2-like protein 1; regulatory protein SIR2 homolog 1; NAD-dependent deacetylase sirtuin-1; sirtuin 1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1], [SIRT1; SIRT1; SIR2L1; SIR2L1; hSIRT1; hSIR2; 75SirT1]
Gene, Accession #[SirT1], Gene ID: 23411, NCBI: NP_001135970.1, UniProt: Q96EB6
Catalog #MBS004131
Price$440, $715
Order / More InfoRabbit SirT1 (Ab-47) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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