Human Bcl-xL Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Bcl-xL antibody, protein, ELISA kits.
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| Antigenic Specificity | Human Bcl-xL |
| Clone | [7B2.5] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG3 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunohistochemistry; Immunoprecipitation; Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human Bcl-xL (Mr 29 kDa). Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems.1 It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment.2 Bcl- 2 and one of its homologues, Bcl-xL, protect cells from apoptosis3,4, while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis.5-8 Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, off |
| Immunogen | Immunogen: Recombinant Bcl-xS |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS670001 |
| Price | $395 |
| Order / More Info | Human Bcl-xL Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cohen, J.J. 1991. Adv. Immunol. 50:55.2. Cohen, J.J., and R.C. Duke. 1992. Annu. Rev. Immunol. 10:2676.3. Nunez, G., and M.F. Clarke. 1994. Trends Cell Biol. 4:399.4. Cory, S. 1995. Annu. Rev. Immunol. 13:513.5. Oltvai., Z.N., C.L. Millman, and S.J. Korsmeyer. 1993. Cell 74:609.6. Farrow, S.N., et al. 1995. Nature 374:731.7. Chittenden, T., et al. 1995. Nature 374:733.8. Kiefer, M.C., et al. 1995. Nature 374:736.9. Boise, L.H., M. Gonzalez-Garcia, C.E. Postema, L. Ding, T. Lindstein, L.A. Turka, X. Mao, G. Nunez, and C.B. Thompson 1993. Cell 74:597.10. Gottschalk, A.R., L.H. Boise, C.B. Thompson, and J. Quintans. 1994. Proc. Natl. Acad. Sci. USA 91:7350.11. Gonzalez-Garcia, M., I. Garcia, L. Ding, S. O'Shea, L.H. Boise, C.B. Thompson, and G. Nunez. 1995. Proc. Natl. Acad. Sci. USA 92:430412. Dole, M.G., R. Jasty, M.J. Cooper, C.B. Thompson, G. Nunez, and V.P. Castle. 1995. Can. Res. 55:2576.13. Shimizu, S., et al. 1995. Nature 374:811.14. Yin, X.M., Z.N. Oltvai, and S.J. Korsmeyer. 1994. Nature 369:321.15. Cheng, E.H.-Y., et al. 1996. Nature 379:554.16. Gottschalk, A.R., L.H. Boise, Z.N. Oltvai, M.A. Accavitti, S.J. Korsmeyer, J. Quintans, and C.B. Thompson. 1996. Cell Death and Differentiation 3:113.17. Boise, L.H. 1997. Personal communication.18. L. Haughan. 1997. Personal communication. |
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MYBIOSOURCE INC.
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