CD40 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CD40 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD40 Ligand (CD40L), a member of the TNF superfamily of ligands, is expressed as either a membrane-bound or soluble homotrimer (1). Both membrane-bound and soluble forms of CD40L have biological activity (1, 2). CD40L is expressed primarily on activated T cells; however, mast cells, basophils, and NK cells may also express CD40L (1). CD40L functions as an important T cell co-stimulatory molecule and enhances T-dependent B cell responses (1, 2). CD40L binds CD40, which is a receptor expressed on B cells, dendritic cells, and macrophages (1). Binding of CD40L to CD40 leads to the recruitment of TRAF proteins (TRAFs 2, 3, 5, and 6) resulting in the activation of the JNK and NF-kappaB pathways (1, 2). |
| Immunogen | Immunogen: C term-peptide of human CD40 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CD40; Bp50; CDW40; MGC9013; TNFRSF5; p50] |
| Gene, Accession # | [CD40], Gene ID: 958, NCBI: NP_001241.1, UniProt: P25942 |
| Catalog # | MBS8505667 |
| Price | $310 |
| Order / More Info | CD40 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. van Kooten, C. and Banchereau, J. (2000) J Leukoc Biol 67, 2-17. 2. Peters, A.L. et al. (2009) Semin Immunol 21, 293-300. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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