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Antigenic Specificity | TGFA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transforming growth factor alpha (TGF-alpha) is a member of the epidermal growth factor (EGF) family, sharing the same receptor, EGFR, and regulating cell proliferation, survival, and differention (1). Members of the family share an EGF-like domain of 45-60 amino acids characterized by the conservation of six regularly spaced cysteins, forming three disulfide bonds that function as their receptor binding domain. TGF-alpha was initially discovered in the media of retrovirally transformed fibroblasts, and it name comes from its ability to induce transformation in cultured fibroblasts (2). This transforming activity was later shown to require TGF-beta, which potentiates the activity of TGF-alpha through a separate receptor (3). Soluble TGF-alp |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Pro-TGF-alpha: TFGA; Pro-TGF-alpha; TGF-alpha], [TGFA; TGFA; TFGA; TGF-alpha; ETGF] |
Gene, Accession # | [TGFA], Gene ID: 7039, NCBI: P01135.1, UniProt: P01135 |
Catalog # | MBS126860 |
Price | $200, $275, $430 |
Order / More Info | TGFA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |