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Antigenic Specificity | Human CD257 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises CD257 (also known as BLyS, BAFF, TALL-1 and THANK), a novel member of the tumor necrosis factor (TNF) superfamily. CD257 and its receptor TACI/BCMA are involved in the development of autoimmune diseases. CD257 has been shown to activate NFkB and JNK (c-jun N-terminal kinase) and induce apoptosis. MBS221636 recognises CD257 (also known as BLyS, BAFF, TALL-1 and THANK), a novel member of the tumor necrosis factor (TNF) superfamily. CD257 and its receptor TACI/BCMA are involved in the development of autoimmune diseases. CD257 has been shown to activate NFkB and JNK (c-jun N-terminal kinase) and induce apoptosis. |
Immunogen | Immunogen: Peptide corresponding to amino acids 254-269 of human CD257 (BAFF). Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to CD257 (BAFF) were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography. Target Species: Human |
Other Names | [tumor necrosis factor ligand superfamily member 13B isoform 2; Tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor ligand superfamily member 13B; ApoL related ligand TALL-1; B-cell-activating factor; B-lymphocyte stimulator; Delta4 BAFF; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; delta BAFF; dendritic cell-derived TNF-like molecule; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor-like protein ZTNF4; tumor necrosis factor (ligand) superfamily, member 13b; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD_antigen: CD257Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form], [TNFSF13B; TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1] |
Gene, Accession # | [CD257], Gene ID: 10673, NCBI: NP_001139117.1, UniProt: Q9Y275 |
Catalog # | MBS221636 |
Price | $375 |
Order / More Info | Human CD257 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |