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Antigenic Specificity | Mouse/Human CD11b |
Clone | [M1/70] |
Host Species | Rat |
Reactive Species | mouse, human |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11b is a 170 kD glycoprotein also known as alphaM integrin, Mac-1 alpha subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (beta2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. |
Immunogen | n/a |
Other Names | [Mouse/Human CD11b; Integrin alpha-M; Itgam; CD11 antigen-like family member B; CR-3 alpha chain; Leukocyte adhesion receptor MO1; CD11b] |
Gene, Accession # | [CD11b], Gene ID: 16409, NCBI: P05555.2, UniProt: P05555 |
Catalog # | MBS2553873 |
Price | $60, $70 |
Order / More Info | Mouse/Human CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Springer TA. 1994. Cell 76:301. 3. Coxon A, et al. 1996. Immunity 5:653. |