Mouse Nlk (C-term), 408-436 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Nlk (C-term), 408-436 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: bovine, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk. Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3. |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase NLK; Nemo-like kinase; Nlk {ECO:0000312|EMBL:AAC244991}] |
| Gene, Accession # | [Nlk], Gene ID: 18099, NCBI: NP_032728.3, UniProt: O54949 |
| Catalog # | MBS9210465 |
| Price | $165, $370 |
| Order / More Info | Mouse Nlk (C-term), 408-436 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Li, M., et al. J. Biol. Chem. 285(18):13397-13404(2010) Nifuji, A., et al. Exp. Cell Res. 316(7):1127-1136(2010) Ishitani, T., et al. Nat. Cell Biol. 12(3):278-285(2010) Martinez, G., et al. Invest. Ophthalmol. Vis. Sci. 50(10):4794-4806(2009) Harwood, B.N., et al. Dev. Dyn. 237(4):1099-1111(2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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