VCAM-1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-VCAM-1 antibody, protein, ELISA kits.
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| Antigenic Specificity | VCAM-1 |
| Clone | [4B9] |
| Host Species | Mouse (Balb/c) |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC), Immunohistochemistry (IHC) (frozen), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody binds exclusively to the cytokine-induced endothelial cell adhesion protein, vascular cell adhesion molecule-1 (VCAM-1). Vascular cell adhesion molecule-1 (VCAM-1) is induced on Human umbilical vein endothelium (HUVE) by recombinant Human tumor necrosis factor - alpha (rh TNF-alpha), rh interleukin-1 (IL-1) and lipopolysaccharide (LPS) and is involved in adherence of lymphocytic cell lines to HUVE. VCAM-1 is only minimally expressed on unstimulated endothelium. Molecular cloning and sequencing of VCAM-1 predicts a 69-kDa core protein with 6 potential N-linked glycosylation sites, if the protein is fully glycosylated a mature protein of about 90kDa is yielded. VCAM-1 mediates a component of the adherence of Peripheral Blood Lymp |
| Immunogen | Source Note: 4B9 is a Mouse IgG1 monoclonal antibody geneRated by immunization of Balb/c mice with Human umbilical vein endothelium (HUVE) that were non-enzymatically harvested after stimulation for 24h with recombinant Human (rh) TNF-alpha (10 ng/ml). Splenocytes were fused with the NS-1 nonsecretory murine myeloma line. |
| Other Names | [vascular cell adhesion protein 1; Vascular cell adhesion protein 1; vascular cell adhesion protein 1; VCAM-1; V-CAM 1; vascular cell adhesion molecule 1], [Vcam1; Vcam1; VCAM1B; Vcam-1; V-CAM 1; VCAM-1] |
| Gene, Accession # | Gene ID: 25361, NCBI: NP_037021.1, UniProt: P29534 |
| Catalog # | MBS570289 |
| Price | $415 |
| Order / More Info | VCAM-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Carlos. T., Schwartz. B., Kovach. N., Yee. E., Rosa. M., Osborn. L., Chi-Rosso. G., Newman. B., Lobb. R., et al. (1990). Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured Human endothelial cells Blood. 76(5) 965-70. Ockenhouse, C.F., Tegoshi, T., Maeno, Y., Benjamin, C., Ho, M., Kan, K.E., Thway, Y., Win, K., Aikawa, M. and Lobb, R.R. (1992). Human vascular endothelial cell adhesion receptors for Plasmodium falciparum-infected erythrocytes: roles for endothelial leukocyte adhesion molecule 1 and vascular cell adhesion molecule 1. J Exp Med. 176, 1183-9. Bacchi, C.E., Marsh, C.L., Perkins, J.D., Carithers, R.L. Jr, McVicar, J.P., Hudkins, K.L., Benjamin, C.D., Harlan, J.M., Lobb, R. and Alpers, C.E. (1993). Expression of vascular cell adhesion molecule (VCAM-1) in liver and pancreas allograft rejection. Am J Pathol. 142, 579-91. Pinola, M., Saksela, E., Tiisala, S. and Renkonen, R. (1994). Human NK cells expressing alpha 4 beta 1/beta 7 adhere to VCAM-1 without preactivation. Scand J Immunol. 39, 131-6. Chuluyan, H.E., Osborn, L., Lobb, R. and Issekutz AC. (1995). Domains 1 and 4 of vascular cell adhesion molecule-1 (CD106) both support very late activation antigen-4 (CD49d/CD29)-dependent monocyte trans-endothelial migRation. J Immunol. 155, 3135-4. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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