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Antigenic Specificity | IRF4 (Center), 164-191 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-191 amino acids from the Central region of human IRF4. The protein encoded by this gene belongs to the IRF(interferon regulatory factor) family of transcription factors,characterized by an unique tryptophan pentad repeat DNA-bindingdomain. The IRFs are important in the regulation of interferons inresponse to infection by virus, and in the regulation ofinterferon-inducible genes. This family member is lymphocytespecific and negatively regulates Toll-like-receptor (TLR)signaling that is central to the activation of innate and adaptiveimmune systems. A chromosomal translocation involving this gene andth |
Immunogen | n/a |
Other Names | [Interferon regulatory factor 4; IRF-4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5; IRF4; MUM1] |
Gene, Accession # | [IRF4], Gene ID: 3662, NCBI: NP_001182215.1, UniProt: Q15306 |
Catalog # | MBS9208400 |
Price | $165, $370 |
Order / More Info | IRF4 (Center), 164-191 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) Staudt, V., et al. Immunity 33(2):192-202(2010) Newton-Bishop, J.A., et al. Cancer Epidemiol. Biomarkers Prev. 19(8):2043-2054(2010) Duffy, D.L., et al. Am. J. Hum. Genet. 87(1):6-16(2010) Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) : |