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Antigenic Specificity | MYH7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MYH7 protein. Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human myosin, heavy chain 7, cardiac muscle, beta |
Other Names | [CMH1; MPD1; SPMD; SPMM; CMD1S; MYHCB] |
Gene, Accession # | [MYH7], Gene ID: 4625, NCBI: NP_000248.2, UniProt: P12883 |
Catalog # | MBS9411905 |
Price | $255 |
Order / More Info | MYH7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |