PION, 770-820 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PION, 770-820 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PION, 770-820 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF, IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Multiple isoforms of PION are known to exist. PION antibody is predicted to not cross-react with other F-box protein family members. PION Antibody: Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by one of two beta-secretases (BACE and BACE2), producing a soluble derivative of the protein and a membrane anchored 99 -amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the Alzheimer's disease patient's brains. PION, or GSAP, selectively increases amyloid-beta production t |
| Immunogen | Immunogen: PION antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PION. |
| Other Names | [PION; PION; PION; Gamma-secretase-activating protein; Protein pigeon homolog; GSAP; pigeon homolog (Drosophila)], [GSAP; GSAP; PION; PION; GSAP; GSAP-16K] |
| Gene, Accession # | [PION], Gene ID: 54103, NCBI: NP_059135, UniProt: A4D1B5 |
| Catalog # | MBS151476 |
| Price | $375 |
| Order / More Info | PION, 770-820 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies