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Antigenic Specificity | MAPT/Tau |
Clone | [MCA-2E9] |
Host Species | Mouse |
Reactive Species | humanpredicted: mouse, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Clone 2E9 is known to react with tau from human, mouse and rat. Since tau is highly conserved, it is likely that the antibody is effective on other species also. Tau promotes microtubule assembly and stability, and might be involvedin the establishment and maintenance of neuronal polarity. the C-terminus binds axonal microtubules while the N-terminus binds neuralplasma membrane components, suggesting that tau functions as a linkerprotein between both. Axonal polarity is predetermined by taulocalization (in the neuronal cell) in the domain of the cell body defined by the centrosome. |
Immunogen | Immunogen: Our antibody was made against a recombinant construct expressed in and purified from E. coli and which corresponded to the shortest version of the various tau proteins, so the antibody is expected to bind to all tau isoforms. Conjugation: Unconjugated |
Other Names | [Rabbit to Human MAPT/Tau; MAPT; FTDP-17; MSTD; Neurofibrillary tangle protein; PHF-tau; MTBT2; PPND; DDPAC; MAPTL; MTBT1; Paired helical filament-tau; TAU] |
Gene, Accession # | [MAPT/Tau], Gene ID: 4137 |
Catalog # | MBS2401538 |
Price | $530 |
Order / More Info | MAPT/Tau Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |