Presenilin 1, Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPresenilin 1,
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, primate, rat
Isotypen/a
Formatunconjugated
Size0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2). Presenilins form the catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Evidence suggests cleavage of APP by gamma-secretase and the production of Abeta (42 aa) is likely to play a important or casual role in the development of Alzheimer's disease.
ImmunogenImmunogen: Peptide corresponding to residues around valine 293 of human presenilin 1
Other Names[Presenilin-1; Presenilin-1; presenilin-1; presenilin 1; Protein S182], [PSEN1; PSEN1; AD3; FAD; PS1; PS-1; S182; AD3; PS1; PSNL1; PS-1; PS1-CTF12]
Gene, Accession #Gene ID: 5663, NCBI: P49768.1
Catalog #MBS555285
Price$450
Order / More InfoPresenilin 1, Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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