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Antigenic Specificity | alpha synuclein (116-131) |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antiserum specifically detects alpha synuclein. Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. Alpha synuclein has been associated with several neurodegenerative diseases. A point mutation in the gene coding for the alpha-synuclein protein was the first discovery linking this protein to a rare familial form of Parkinson's disease (PD). Subsequently, other mutations in the alpha-synuclein gene have been identified in familial PD. The aggregated proteinaceous inclusions called Lewy bodies found in PD and cortical Lewy body dementia (LBD) were discovered to be predominantly alpha-synuclein. Aberrant aggregation of alpha-synuclein has been detected |
Immunogen | Immunogen: A synthetic peptide (CMPVDPDNEAYEMPSEE) of human alpha synuclein protein (aa: 116-131) conjugated to diphtheria toxoid has been used as the immunogen. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | [alpha synuclein, partial; Alpha-synuclein; alpha-synuclein; synuclein alpha; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP] |
Gene, Accession # | Gene ID: 6622, NCBI: AAS83394.1 |
Catalog # | MBS4152771 |
Price | $515 |
Order / More Info | alpha synuclein (116-131) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |