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Antigenic Specificity | MMP9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein ( |
Immunogen | Immunogen: A synthetic peptide of human MMP9 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CLG4B; GELB; MMP-9] |
Gene, Accession # | [MMP9], Gene ID: 4318, NCBI: NP_004985.2, UniProt: P14780 |
Catalog # | MBS8503535 |
Price | $310 |
Order / More Info | MMP9 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. McCawley, L.J. and Matrisian, L.M. (2001) Curr. Opin. Cell Biol. 13, 534-540. 2. Coussens, L.M. et al. (2002) Science 295, 2387-2391. 3. Sternlicht, M.D. et al. (1999) Cell 98, 137-146. 4. Vu, T.H. et al. (1998) Cell 93, 411-422. 5. Nagase, H. et al. (1990) Biochemistry 29, 5783-5789. |