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Antigenic Specificity | Mouse ITGAM / CD11b |
Clone | [M1/70.15] |
Host Species | Rat |
Reactive Species | human, mouse, rabbit |
Isotype | IgG2b |
Format | ion exchange purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. This product is routinely tested in flow cytometry on mouse peritoneal macrophages. The leukocyte adhesion receptor Mac-1 is a cell surface glycoprotein that plays a fundamental role in the adhesion between myeloid and lymphoid cells. It is composed of alpha/beta heterodi |
Immunogen | Immunogen Description: T cell enriched splenocytes from B10 mice. |
Other Names | [ITGAM / CD11b (clone M1/70.15) IHC-plus; ITGAM; Antigen CD11b (p170); CD11B; CD11b antigen; CR3A; Integrin alpha-M; MAC-1; MO1A; Neutrophil adherence receptor; MAC1A; SLEB6; CR-3 alpha chain; Mouse ITGAM; CD11b], [CD11b] |
Gene, Accession # | [ITGAM], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
Catalog # | MBS246285 |
Price | $530 |
Order / More Info | Mouse ITGAM / CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |