Smac/DIABLO Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySmac/DIABLO
Clone[79-1-83]
Host SpeciesMouse
Reactive Specieshuman, monkey
IsotypeIgG2b
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) (PS), Western Blot (WB)
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DescriptionRecognizes human and monkey Smac/DIABLO. Smac/DIABLO is one of the pro-apoptotic proteins normally found in the intermembrane space of the mitochondria. In response to apoptotic stimuli, Smac/DIABLO is released into the cytosol resulting in permeabilization of the mitochondrial membrane. Cytosolic Smac/DIABLO activates caspase-9 by binding IAP proteins. Changes in the expression level of Smac/DIABLO have been demonstrated in a number of human cancers including melanoma, ovary, and prostate.
ImmunogenImmunogen: Recombinant full length human Smac/DIABLO.
Other Names[Second mitochondria-derived activator of caspase], [DIABLO; DIABLO; SMAC; DFNA64; SMAC; Smac]
Gene, Accession #[Smac/DIABLO], Gene ID: 56616, NCBI: Q9NR28.1, UniProt: Q9NR28
Catalog #MBS565110
Price$345
Order / More InfoSmac/DIABLO Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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