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Antigenic Specificity | Smac/DIABLO |
Clone | [79-1-83] |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | IgG2b |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) (PS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human and monkey Smac/DIABLO. Smac/DIABLO is one of the pro-apoptotic proteins normally found in the intermembrane space of the mitochondria. In response to apoptotic stimuli, Smac/DIABLO is released into the cytosol resulting in permeabilization of the mitochondrial membrane. Cytosolic Smac/DIABLO activates caspase-9 by binding IAP proteins. Changes in the expression level of Smac/DIABLO have been demonstrated in a number of human cancers including melanoma, ovary, and prostate. |
Immunogen | Immunogen: Recombinant full length human Smac/DIABLO. |
Other Names | [Second mitochondria-derived activator of caspase], [DIABLO; DIABLO; SMAC; DFNA64; SMAC; Smac] |
Gene, Accession # | [Smac/DIABLO], Gene ID: 56616, NCBI: Q9NR28.1, UniProt: Q9NR28 |
Catalog # | MBS565110 |
Price | $345 |
Order / More Info | Smac/DIABLO Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |