Human CD274 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD274 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | reacts with: mouse, rat. |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Paraffin*, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item detects CD274, also known as B7-H1 and PD-1L, a cell surface glycoprotein which is a member of the B7 family of co-stimulatory molecules. CD274 is expressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells, endothelial cells and epithelial cells in response to Interferons alpha, beta and gamma. . . CD274 is reported to possess dual functions; inhibition of activated effector T cells and co-stimulation of naive T cells. CD274 inhibits proliferation of activated T cells via ligation to the co-inhibitory molecule CD279 (programmed death-1; PD-1) leading to the secretion of the regulatory cytokine interleukin-10. CD274 has also been shown to co-stimulate early T cell priming and differe |
| Immunogen | Immunogen: A peptide corresponding to a 17 amino acid sequence from near the centre of Human CD274. Histology Positive Control Tissue: Human heart tissue Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Human CD274 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
| Other Names | [programmed cell death 1 ligand 1 isoform b; Programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; CD274 molecule; B7 homolog 1; B7-H1; CD_antigen: CD274], [CD274; CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; B7H1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7-H1] |
| Gene, Accession # | [CD274], Gene ID: 29126, NCBI: NP_001254635.1, UniProt: Q9NZQ7 |
| Catalog # | MBS224074 |
| Price | $380 |
| Order / More Info | Human CD274 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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