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Antigenic Specificity | SERPINB6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood By similarity. Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. |
Immunogen | n/a |
Other Names | [serpin B6 isoform a; Serpin B6; serpin B6; cytoplasmic antiproteinase; protease inhibitor 6 (placental thrombin inhibitor); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; Cytoplasmic antiproteinase; CAP; Peptidase inhibitor 6; PI-6; Placental thrombin inhibitor], [SERPINB6; SERPINB6; CAP; PI6; PTI; PI-6; SPI3; DFNB91; MSTP057] |
Gene, Accession # | [SERPINB6], Gene ID: 5269, NCBI: NP_001258754.1 |
Catalog # | MBS416644 |
Price | $230 |
Order / More Info | SERPINB6 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Sirmaci,A., Erbek,S., Price,J., et al. A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss. Am. J. Hum. Genet. 86 (5), 797-804 (2010) |