Human GRM5 / MGLUR5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human GRM5 / MGLUR5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | Bat, Gibbon, bovine, chicken, dog, hamster, horse, human, monkey, mouse, porcine, rabbit, rat. predicted reactivity: Xenopus (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human GRM5 / MGLUR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. |
| Immunogen | Immunogen Description: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GRM5 / MGLUR5. |
| Other Names | [GRM5 / MGLUR5 (N-Terminus) IHC-plus; GRM5; GPRC1E; MGLUR5; Mglur5b; MGlu5; Human GRM5; MGLUR5], [MGLUR5] |
| Gene, Accession # | [GRM5], Gene ID: 2915, NCBI: NP_000833.1, UniProt: P41594 |
| Catalog # | MBS240873 |
| Price | $530 |
| Order / More Info | Human GRM5 / MGLUR5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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