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Antigenic Specificity | RAP2A (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 124-159 amino acids from human RAP2A. Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Ras-related protein Rap-2a; RbBP-30; RAP2A] |
Gene, Accession # | [RAP2A], Gene ID: 5911, NCBI: NP_066361.1, UniProt: P10114 |
Catalog # | MBS9216459 |
Price | $165, $370 |
Order / More Info | RAP2A (C-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Pizon V.,et al.Oncogene 3:201-204(1988).Fan Z.S.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).Dunham A.,et al.Nature 428:522-528(2004). |