TFEB (Center), 271-300 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TFEB (Center), 271-300 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.44 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This TFEB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human TFEB. Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It ther |
| Immunogen | n/a |
| Other Names | [Transcription factor EB; Class E basic helix-loop-helix protein 35; bHLHe35; TFEB; BHLHE35] |
| Gene, Accession # | [TFEB], Gene ID: 7942, NCBI: NP_001161299.2, UniProt: P19484 |
| Catalog # | MBS9206773 |
| Price | $165, $370 |
| Order / More Info | TFEB (Center), 271-300 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Martignoni, G., et al. Mod. Pathol. 22(8):1016-1022(2009) Sardiello, M., et al. Science 325(5939):473-477(2009) Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008) Pecciarini, L., et al. Genes Chromosomes Cancer 46(5):419-426(2007) Argani, P., et al. Am. J. Surg. Pathol. 29(2):230-240(2005) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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