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Antigenic Specificity | Tyrosine Hydroxylase, phosphorylated |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunofluroescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the rat ~60kD tyrosine hydroxylase protein, phosphorylated at Ser40 and does not react with the non-phosphorylated form of the TH protein. Reactivity has been confirmed in rat PC-12 cell lysates stimulated with okadaic acid. Tyrosine hydroxylase (TH, tyrosine 3-monooxygenase) is the eukaryotic enzyme that catalyzes the first, rate-limiting step in the biosynthesis of dopamine and other catecholamines from tyrosine.1 TH requires O2 and ferrous iron for the hydroxylation reaction it catalyzes. In mammals, TH is encoded by a single gene that is required for embryonic development and survival;2 full-length cDNA for this enzyme has been obtained for rat, mouse, bovine, Drosophila, macaque monkey, and human species.3 In all vertebrates |
Immunogen | Immunogen: Synthetic phospho-peptide derived from the rat tyrosine hydroxylase phosphorylated (Ser40). |
Other Names | Tyrosine Hydroxylase, phosphorylated (Ser40) (TH, TYH, Tyrosine 3 Hydroxylase, Tyrosine 3 Monooxygenase) |
Gene, Accession # | Gene ID: 7054, UniProt: O43816 |
Catalog # | MBS628517 |
Price | $635 |
Order / More Info | Tyrosine Hydroxylase, phosphorylated Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |