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Antigenic Specificity | DUSP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total DUSP10 protein. Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human dual specificity phosphatase 10 |
Other Names | [MKP5; MKP-5] |
Gene, Accession # | [DUSP10], Gene ID: 11221, NCBI: NP_009138.1, UniProt: Q9Y6W6 |
Catalog # | MBS9413225 |
Price | $255 |
Order / More Info | DUSP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |