DUSP10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDUSP10
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total DUSP10 protein. Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human dual specificity phosphatase 10
Other Names[MKP5; MKP-5]
Gene, Accession #[DUSP10], Gene ID: 11221, NCBI: NP_009138.1, UniProt: Q9Y6W6
Catalog #MBS9413225
Price$255
Order / More InfoDUSP10 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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