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Antigenic Specificity | MPZ - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in- |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MPZ |
Other Names | [myelin protein P0 isoform MPZ; Myelin protein P0; myelin protein P0; myelin protein zero; Myelin peripheral protein; MPP; Myelin protein zero] |
Gene, Accession # | [MPZ], Gene ID: 4359, NCBI: NP_000521.2, UniProt: P25189 |
Catalog # | MBS3220772 |
Price | $335 |
Order / More Info | MPZ - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |