MPZ - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMPZ - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human MPZ
Other Names[myelin protein P0 isoform MPZ; Myelin protein P0; myelin protein P0; myelin protein zero; Myelin peripheral protein; MPP; Myelin protein zero]
Gene, Accession #[MPZ], Gene ID: 4359, NCBI: NP_000521.2, UniProt: P25189
Catalog #MBS3220772
Price$335
Order / More InfoMPZ - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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