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Antigenic Specificity | Human CD58(LFA-3) |
Clone | [TS2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 0.1 mg |
Concentration | 1.0 mg/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Information: Human CD58 is a cell surface glycoprotein that functions as an adhesion molocule and mediates costimulatory activity through its ligand CD2, which is expressed on T and natural killer cells (1,2). CD58 has wide cellular distribution on both hemopoietic and non-hemopoietic cells with strong expression on macrophages and memory T cells. Antibody TS2 recognizes the CD58 glycoprotein of about 60-70 kd and will inhibit HLA-DR mediated T cell cytotoxicity. |
Immunogen | Immunogen: Human cytotoxic T cells |
Other Names | [human CD58(LFA-3)], [CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3] |
Gene, Accession # | [CD58], Gene ID: 965, NCBI: CAG33220.1, UniProt: P19256 |
Catalog # | MBS666218 |
Price | $270 |
Order / More Info | Human CD58(LFA-3) Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997)p. 414-415. (2) A.R. Arulanandam, et al, (1994) J Exp Med 180:1861-1871. |