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Antigenic Specificity | Human Lactate Dehydrogenase A |
Clone | [PAT1A4AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. |
Immunogen | Immunogen: Anti-human LDHA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LDHA amino acids 1-332 purified from E Coli. |
Other Names | [LDHA; Lactate Dehydrogenase A, Mouse Human; LDH-A; GSD11; LDH1; LDHM; PIG19; EC 1.1.1.27; lactate dehydrogenase M; LDH-M; LDH-1; L-lactate dehydrogenase A chain; LDH muscle subunit; Renal carcinoma antigen NY-REN-59; Cell proliferation-inducing gene 19 protein; LDHA], [LDHA; LDHA; LDH1; LDHM; GSD11; PIG19; HEL-S-133P; LDH-A; LDH-M] |
Gene, Accession # | [LDHA], Gene ID: 3939, NCBI: NP_001128711.1 |
Catalog # | MBS140341 |
Price | $140, $205, $505 |
Order / More Info | Human Lactate Dehydrogenase A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |