Mouse CD253 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD253 |
| Clone | [N2B2] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.5mg/ml |
| Applications | Flow cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises mouse CD253, also known as TNF-related apoptosis-inducing ligand or TRAIL, a member of the tumour necrosis factor ligand superfamily. When bound to the death receptors DR4 and DR5 caspase-8-dependent apoptosis is induced. However, CD253 might also be bound by the decoy receptor DcR1 which cannot induce apoptosis, and DcR2 which activates NF-kappa-B. . . Clone N2B2 has been reported to block NK cell cytotoxicity in vitro. MBS219793 recognises mouse CD253, also known as TNF-related apoptosis-inducing ligand or TRAIL, a member of the tumour necrosis factor ligand superfamily. When bound to the death receptors DR4 and DR5 caspase-8-dependent apoptosis is induced. However, CD253 might also be bound by the decoy receptor Dc |
| Immunogen | Immunogen: Mouse CD253-transfected 2PK-3 cells Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [tumor necrosis factor ligand superfamily member 10; Tumor necrosis factor ligand superfamily member 10; tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis-inducing ligand; TRAIL/APO2L; tumor necrosis factor (ligand) superfamily, member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD_antigen: CD253], [Tnfsf10; Tnfsf10; TL2; Ly81; Trail; APO-2L; AI448571; A330042I21Rik; Trail; Protein TRAIL] |
| Gene, Accession # | [CD253], Gene ID: 22035, NCBI: NP_033451.1, UniProt: P50592 |
| Catalog # | MBS219793 |
| Price | $300 |
| Order / More Info | Mouse CD253 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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