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Antigenic Specificity | PIK3AP1 (C-term), 639-668 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PIK3AP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-668 amino acids from the C-terminal region of human PIK3AP1. PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity). |
Immunogen | n/a |
Other Names | [Phosphoinositide 3-kinase adapter protein 1; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1; PIK3AP1; BCAP] |
Gene, Accession # | [PIK3AP1], Gene ID: 118788, NCBI: NP_689522.2, UniProt: Q6ZUJ8 |
Catalog # | MBS9212195 |
Price | $165, $370 |
Order / More Info | PIK3AP1 (C-term), 639-668 Antibody from MYBIOSOURCE INC. |
Product Specific References | Koutros, S., et al. Cancer Res. 70(6):2389-2396(2010) Rikova, K., et al. Cell 131(6):1190-1203(2007) Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006) Maruoka, M., et al. FEBS Lett. 579(14):2986-2990(2005) Okada, T., et al. Immunity 13(6):817-827(2000) |