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Antigenic Specificity | CDKN1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.6mg/ml |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and |
Immunogen | Immunogen: Fusion protein of human CDKN1A Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3 |
Other Names | [P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1] |
Gene, Accession # | [CDKN1A], Gene ID: 1026 |
Catalog # | MBS2542361 |
Price | $110, $150, $225 |
Order / More Info | CDKN1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |