ITGAM Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ITGAM |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ITGAM antibody detects endogenous levels of total ITGAM. Description: ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. It is also a receptor for fibrinogen, factor X and ICAM1. ITGAM recognizes P1 and P2 peptides of fibrinogen gamma chain.Function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the upta |
| Immunogen | Immunogen: A synthesized peptide derived from human ITGAM Subcellular Location: Plasma Membrane Tissue Specificity: Predominantly expressed in monocytes and granulocytes (PubMed:1346576). Expressed in neutrophils (at protein level) (PubMed:21193407). Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (88%), Horse (86%), Sheep (88%), Rabbit (88%), Dog (88%) |
| Other Names | [antigen CD11b (p170); Antigen CD11b p170; CD11 antigen like family member B; CD11 antigen-like family member B; CD11b; CD11b/CD18; CD49d; Cell surface glycoprotein MAC-1 subunit alpha; Complement component 3 receptor 3 subunit; Complement Component Receptor 3 Alpha; Complement receptor type 3, alpha subunit; CR 3 alpha chain (CR3A); CR 3 alpha chain; CR-3 alpha chain; CR3; CR3A; F730045J24Rik; Integrin Alpha M; Integrin alpha M chain; Integrin alpha-M; Integrin beta 2 alpha subunit; Integrin subunit alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITAM_HUMAN; ITGAM; Leukocyte adhesion receptor MO1; Ly-40; MAC 1; Mac-1a; MAC1; Mac1, alpha subunit; MAC1A; Macrophage antigen alpha polypeptide; MGC117044; Mo1, alpha subunit; MO1A; Neutrophil adherence receptor alpha M subunit; Neutrophil adherence receptor; SLEB6] |
| Gene, Accession # | [ITGAM], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
| Catalog # | MBS9607132 |
| Price | $240, $280 |
| Order / More Info | ITGAM Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yan J, Yang X, Han D, Feng J; Journal: Mol Med Rep. Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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