Edit |   |
---|---|
Antigenic Specificity | TIA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Nucleolysin TIA-1 isoform p40(TIA1) detection. Tested with WB in Human, Mouse. Background: TIA1, also called WDM, encodes an RNA-binding protein involved in splicing regulation and translational repression. The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte(CTL) target cells. By in situ hybridization, this gene is mapped to chromosome 2p13.3. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is though to be deri |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TIA1 (98-110aa STQRSQDHFHVFV), identical to the related mouse sequence. |
Other Names | [Nucleolysin TIA-1 isoform p40; TIA1 cytotoxic granule-associated RNA binding protein; Cytotoxic granule associated RNA binding protein 1; Cytotoxic granule associated RNA binding protein; mTIA-1; Nucleolysin TIA 1 isoform p40; Nucleolysin TIA-1 isoform p40; Nucleolysin TIA1 isoform p40 p40 TIA 1; p40-TIA-1(containing p15-TIA-1); p40-TIA-1; RNA binding protein TIA 1; RNA binding protein TIA1; RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA 1; TIA 1 cytotoxic granule associated RNA binding protein; Tia; TIA-1; TIA1; TIA1 cytotoxic granule associated RNA binding protein; TIA1 cytotoxic granule associated RNA binding protein like 1; TIA1 protein; TIA1_HUMAN; TIAL1; TIAR], [TIA1; TIA1; WDM; TIA-1; TIA-1] |
Gene, Accession # | [TIA1], Gene ID: 7072, NCBI: P31483.3, UniProt: P31483 |
Catalog # | MBS176792 |
Price | $280 |
Order / More Info | TIA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |