Edit |   |
---|---|
Antigenic Specificity | CYR61 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Biological Significance: Cyr61 is a secreted heparin binding protein, encoded by a growth factor-inducible immediate-early gene, that associates with the extracellular matrix and connective tissue. As an angiogenic inducer, Cyr61 binds to the cell surface receptor Integrin aV/b3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells.Implications In Disease: Cyr61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression. |
Immunogen | Immunogen: CYR61 antibody was raised in rabbit using recombinant human CYR61 protein as the immunogen. |
Other Names | [Affinity Purified Rabbit CYR61; Human CYR61; CYR61; IGFBP10; IGF binding protein 10; IBP10; CCN family member 1; CCN1] |
Gene, Accession # | [CYR61], Gene ID: 3491 |
Catalog # | MBS5316442 |
Price | $460 |
Order / More Info | CYR61 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |