BBS5 (Center) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | BBS5 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: monkey, mouse) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This BBS5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-141 amino acids from the Central region of human BBS5. The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 |
| Immunogen | n/a |
| Other Names | [Bardet-Biedl syndrome 5 protein; BBS5] |
| Gene, Accession # | [BBS5], Gene ID: 129880, NCBI: NP_689597.1, UniProt: Q8N3I7 |
| Catalog # | MBS9214694 |
| Price | $165, $370 |
| Order / More Info | BBS5 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Li J.B.,et al.Cell 117:541-552(2004). Bechtel S.,et al.BMC Genomics 8:399-399(2007). Hillier L.W.,et al.Nature 434:724-731(2005). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Badano J.L.,et al.Nature 439:326-330(2006). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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