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Antigenic Specificity | KCNQ4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KCNQ4 Polyclonal Antibody detects endogenous levels of KCNQ4 protein. Potassium voltage-gated channel subfamily KQT member 4 encoded by KCNQ4 forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progress |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human KCNQ4 at AA range: 620-700 |
Other Names | [Rabbit KCNQ4; KCNQ4; Potassium voltage-gated channel subfamily KQT member 4; KQT-like 4; Potassium channel subunit alpha KvLQT4; Voltage-gated potassium channel subunit Kv7.4] |
Gene, Accession # | [KCNQ4], Gene ID: 9132, NCBI: NP_004691.2, UniProt: P56696 |
Catalog # | MBS9702367 |
Price | $130, $220, $325 |
Order / More Info | KCNQ4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |