Human LAT1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Human LAT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | no preservative |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Immunohistology Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti Human LAT1 antibody specifically recognizes human LAT1 (L-type amino acid transporter 1), a heterodimeric Na+-independent amino acid transporter protein and member of the amino acid-polyamine-organocation (APC) superfamily, involved in the high-affinity transport of large neutral amino acids, in association with SLC3A2/4F2hc. LAT1 is highly expressed in the brain and is involved in the transport of L-DOPA across the blood-brain barrier, in brain neurogenesis, and acts as a mediator of L-leucine transport across the inner blood-retinal barrier. LAT1 is involved in the cell membrane transport of the thyroid hormones triiodothyronine (T3) and thyroxine (T4) in the placenta, and is the foremost transporter of tyrosine in fibroblasts |
| Immunogen | Immunogen: Keyhole limpet haemocyanin (KLH) conjugated synthetic peptide C-RHRKPEL, representing a portion of human LAT1. Histology Positive Control Tissue: Breast Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human Lat1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
| Other Names | [large neutral amino acids transporter small subunit 1; Large neutral amino acids transporter small subunit 1; large neutral amino acids transporter small subunit 1; 4F2 LC; 4F2 light chain; CD98 light chain; L-type amino acid transporter 1; integral membrane protein E16; large neutral amino acids transporter 1; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; solute carrier family 7 member 5; y+ system cationic amino acid transporter; solute carrier family 7 (amino acid transporter light chain, L system), member 5; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter], [SLC7A5; SLC7A5; E16; CD98; LAT1; 4F2LC; MPE16; hLAT1; D16S469E; CD98LC; LAT1; MPE16; 4F2 LC; 4F2LC; hLAT1] |
| Gene, Accession # | [LAT1], Gene ID: 8140, NCBI: NP_003477.4, UniProt: Q01650 |
| Catalog # | MBS223769 |
| Price | $375 |
| Order / More Info | Human LAT1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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