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Antigenic Specificity | STAT3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214). May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1 (PubMed:17344214). Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity). May |
Immunogen | Immunogen: Recombinant human Signal transducer and activator of transcription 3 protein (50-240AA) |
Other Names | [Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3] |
Gene, Accession # | [STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763 |
Catalog # | MBS7043946 |
Price | $160, $235 |
Order / More Info | STAT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |