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Antigenic Specificity | TUBB2b |
Clone | [AT5B3] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. Multiple beta Tubulin isoforms have been characterized and are expressed in mammalian tissues. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2b is mainly expressed in developing neurons with a dominant expression during the critical steps of corticogenesis. Also, TUBB2B is a new critical gene involved in neuronal migration. It is present in the nuclei and nucleoplasm, Defects in this gene are a cause of asymmetric polymicrogyria. |
Immunogen | Immunogen: Recombinant human TUBB2b (1-445aa) purified from E. coli |
Other Names | [bA506K6.1; DKFZp566F223; FLJ98847; MGC8685; Tubulin beta-2B chain; tubulin beta 2B], [TUBB2B; TUBB2B; CDCBM7; PMGYSA; bA506K6.1] |
Gene, Accession # | [TUBB2b], Gene ID: 347733, NCBI: NP_821080, UniProt: Q9BVA1 |
Catalog # | MBS200174 |
Price | $240, $315 |
Order / More Info | TUBB2b Antibody from MYBIOSOURCE INC. |
Product Specific References | Xavier Hubert Jaglin, et al. (2009) Nat Genet, 41 (6):746-52.; Bouwmeester T, et al. (2004) Nat Cell Bio, 6 (2):97-105.; Modig, C, et al. (1999) Cell Motil Cytoskeleton, 42 (4): 315-330. |