NPM1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNPM1
Clone[1042CT5.2.1]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionSpecificity: Purified His-tagged NPM1 protein was used to produced this monoclonal antibody. Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to rep
Immunogenn/a
Other Names[Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin; NPM1; NPM]
Gene, Accession #[NPM1], Gene ID: 4869, NCBI: NP_001032827.1, UniProt: P06748
Catalog #MBS9200102
Price$165, $370
Order / More InfoNPM1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSwaminathan V., et al. Mol. Cell. Biol. 25:7534-7545(2005). Tago K., et al. Proc. Natl. Acad. Sci. U.S.A. 102:7689-7694(2005). Bolli N., et al. Lancet Oncol. 7:350-352(2006). Lu L., et al. Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. Kalnine N., et al. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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