Human Caspase-3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Caspase-3 |
| Clone | [SB71b1 (5G5A11] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reacts with human Caspase 31The Caspases are a family of cysteine proteases that induce apoptosis in response to a variety of intra- and extracellular stimuli. These enzymes are synthesized as inactive precursors which become cleaved at aspartate-specific sites upon induction of apoptosis. Caspase 3 (CPP32, Yama, apopain) is one of the best characterized caspases in terms of specificity and function in apoptosis. It is a ubiquitously expressed protein in mammals and is highly prevalent in cells with lymphocytic origins, indicating a regulatory role in the immune system. Caspase 3 plays a critical role during embryonic development by inducing morphogenetic cell death in the mammalian brain and has also been linked to chromatin condensation, |
| Immunogen | Immunogen: Recombinant Caspase 3. Characterization: To ensure acceptable performance, each batch of product is tested by Western blotting to conform to characteristics of a standard reference reagent. |
| Other Names | [Mouse Human Caspase 3], [CASP3; CASP3; CPP32; SCA-1; CPP32B; CPP32; CASP-3; CPP-32; SCA-1] |
| Gene, Accession # | Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
| Catalog # | MBS670196 |
| Price | $230 |
| Order / More Info | Human Caspase-3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Krumschnabel, G. et al. (2009). Cell Death and Diff. 16: 195-207.3) Cohen, G.M. (1997). Biochem. J. 326: 1-16.4) Fernandes-Alnemri, T. et al. (1994). J. Biol. Chem. 269: 30761-64.5) Porter, A.G. and Janicke, R.U. (1999). Cell Death and Diff. 6: 99-104.6) Janicke, R.U. et al. (1998). J. Biol. Chem. 273: 9357-60.7) Inbal, B. et al. (2002). J. Cell. Biol. 157: 455-68. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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