ROCK2 (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityROCK2 (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis ROCK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1346-1380 amino acids from the C-terminal region of human ROCK2. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic dif
Immunogenn/a
Other Names[Rho-associated protein kinase 2; Rho kinase 2; Rho-associated; coiled-coil-containing protein kinase 2; Rho-associated; coiled-coil-containing protein kinase II; ROCK-II; p164 ROCK-2; ROCK2; KIAA0619]
Gene, Accession #[ROCK2], Gene ID: 9475, NCBI: NP_004841.2, UniProt: O75116
Catalog #MBS9206549
Price$165, $370
Order / More InfoROCK2 (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesTakahashi N.,et al.Genomics 55:235-237(1999). Ishikawa K.,et al.DNA Res. 5:169-176(1998). Hillier L.W.,et al.Nature 434:724-731(2005). Kawano Y.,et al.J. Cell Biol. 147:1023-1038(1999). Sebbagh M.,et al.J. Exp. Med. 201:465-471(2005).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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