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Antigenic Specificity | SEPT2 (C-term), 280-309 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SEPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human SEPT2. Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongati |
Immunogen | n/a |
Other Names | [Septin-2; Neural precursor cell expressed developmentally down-regulated protein 5; NEDD-5; SEPT2; DIFF6; KIAA0158; NEDD5] |
Gene, Accession # | [SEPT2], Gene ID: 4735, NCBI: NP_001008491.1, UniProt: Q15019 |
Catalog # | MBS9214189 |
Price | $165, $370 |
Order / More Info | SEPT2 (C-term), 280-309 Antibody from MYBIOSOURCE INC. |
Product Specific References | Martins-de-Souza, D., et al. J Psychiatr Res (2010) In press : Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010) Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009) Shen, M., et al. Environ. Mol. Mutagen. 50(4):285-290(2009) Mostowy, S., et al. J. Biol. Chem. 284(17):11613-11621(2009) |