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Antigenic Specificity | TTL - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TTL. It was validated on Western Blot using a cell lysate as a positive control.Target Description: TTL catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM]. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TTL |
Other Names | [tubulin--tyrosine ligase; Tubulin--tyrosine ligase; tubulin--tyrosine ligase; tubulin tyrosine ligase] |
Gene, Accession # | [TTL], Gene ID: 150465, NCBI: NP_714923, UniProt: Q8NG68 |
Catalog # | MBS3211188 |
Price | $335 |
Order / More Info | TTL - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |