Phospho-p47 phox (Ser359) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-p47 phox (Ser359)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Phospho-p47 phox (Ser359) antibody detects endogenous levels of p47 phox only when phosphorylated at Serine 359. Description: The 47-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase is found in neutrophils. The holo-oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Contains 2 SH2 domains.Function: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).Subunit Structure: Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts (via C-terminus) w
ImmunogenImmunogen: A synthesized peptide derived from human p47 phox around the phosphorylation site of Serine 359 Subcellular Location: Cytoplasm. Tissue Specificity: Detected in peripheral blood monocytes and neutrophils (at protein level).
Other Names[47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NCF 47K; NCF-1; NCF-47K; Ncf1; NCF1_HUMAN; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox organizing protein 2; Nox-organizing protein 2; NOXO2; p47 phox; p47-phox; SH3 and PX domain containing protein 1A; SH3 and PX domain-containing protein 1A; SH3PXD1A]
Gene, Accession #[NCF1], Gene ID: 653361, NCBI: NP_000256.4, UniProt: P14598
Catalog #MBS9600938
Price$240, $280
Order / More InfoPhospho-p47 phox (Ser359) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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