RNF20 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-RNF20 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | RNF20 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates |
| Immunogen | Immunogen: A synthesized peptide derived from human RNF20. Subcellular Localization: Nucleus. Tissue Specificity: Expressed in the normal brain and also in malignant gliomas (at protein level). |
| Other Names | [E3 ubiquitin-protein ligase BRE1A; BRE1-A; hBRE1; 6.3.2.-; RING finger protein 20; RNF20; BRE1A], [RNF20; BRE1A; BRE1-A; hBRE1] |
| Gene, Accession # | [RNF20], Gene ID: 56254, NCBI: NP_062538.5, UniProt: Q5VTR2 |
| Catalog # | MBS179963 |
| Price | $160, $340, $340 |
| Order / More Info | RNF20 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies