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Antigenic Specificity | JAM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: JAM1 antibody detects endogenous levels of total JAM1. Function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).Subunit Structure: Interacts with the ninth PDZ domain of MPDZ (PubMed:11489913). Interacts wi |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Junction > Tight Junction. Cell Membrane. Localized at tight junctions of both epithelial and endothelial cells. Tissue Specificity: Expressed in endothelium, epithelium and leukocytes (at protein level). |
Other Names | [CD 321; CD321; CD321 antigen; ESTM33; F11 receptor; F11R; JAM 1; JAM A; JAM; JAM-1; JAM-A; JAM1; JAM1_HUMAN; JAMA; JCAM; Jcam1; Junction adhesion molecule 1; Junction adhesion molecule, mouse, homolog of; Junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM 1; PAM-1; PAM1; Platelet adhesion molecule 1; Platelet adhesion molecule; Platelet F11 receptor; PRO301; UNQ264] |
Gene, Accession # | [JAM1], Gene ID: 50848, NCBI: NP_001335020.1, UniProt: Q9Y624 |
Catalog # | MBS9604063 |
Price | $240, $280 |
Order / More Info | JAM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |