HLA-A (MHC I) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHLA-A (MHC I)
Clone[108-2C5]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF)
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DescriptionSpecificity: HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of the alpha1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited
ImmunogenImmunogen: Normal human peripheral blood lymphocytes
Other Names[HLA-A; HLA class 1A; MHC class I HLA-A], [HLA-B; HLA-B; AS; HLAB; Bw-47; Bw-50; SPDA1; B-4901; B-5001; HLA-Cw; HLA-B15; HLA-B39; HLA-B49; HLA-B50; HLA-B55; HLA-B59; HLA-B61; HEL-S-83; HLA-DRB1; HLA-B*45ZJ; HLA-B-3506; HLA-B-3905; HLA-B-5502; HLA-B-5602; HLAB]
Gene, Accession #[HLA-A], Gene ID: 3106, NCBI: NP_005505.2, UniProt: P01889
Catalog #MBS438658
Price$190, $340, $340
Order / More InfoHLA-A (MHC I) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDomenech N et al. Hum Immunol 1991, 30(2):140-6 Lozano F et al. Immunogenetics 1989, 30::50-3 Lozano F et al. Tissue Antigens 1990, 35:193-5 Young NT et al. Hum Immunol 1997, 52(1):1-11 Krensky AM et al Transplant Proc 1996, 28(6):3026-8 Hansen JA et al Hematol Oncol Clin North Am 1990, 4(3):507-515
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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