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Antigenic Specificity | HLA-A (MHC I) |
Clone | [108-2C5] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of the alpha1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited |
Immunogen | Immunogen: Normal human peripheral blood lymphocytes |
Other Names | [HLA-A; HLA class 1A; MHC class I HLA-A], [HLA-B; HLA-B; AS; HLAB; Bw-47; Bw-50; SPDA1; B-4901; B-5001; HLA-Cw; HLA-B15; HLA-B39; HLA-B49; HLA-B50; HLA-B55; HLA-B59; HLA-B61; HEL-S-83; HLA-DRB1; HLA-B*45ZJ; HLA-B-3506; HLA-B-3905; HLA-B-5502; HLA-B-5602; HLAB] |
Gene, Accession # | [HLA-A], Gene ID: 3106, NCBI: NP_005505.2, UniProt: P01889 |
Catalog # | MBS438658 |
Price | $190, $340, $340 |
Order / More Info | HLA-A (MHC I) Antibody from MYBIOSOURCE INC. |
Product Specific References | Domenech N et al. Hum Immunol 1991, 30(2):140-6 Lozano F et al. Immunogenetics 1989, 30::50-3 Lozano F et al. Tissue Antigens 1990, 35:193-5 Young NT et al. Hum Immunol 1997, 52(1):1-11 Krensky AM et al Transplant Proc 1996, 28(6):3026-8 Hansen JA et al Hematol Oncol Clin North Am 1990, 4(3):507-515 |