Edit |   |
---|---|
Antigenic Specificity | ADAMTS4 |
Clone | [1995CT113.89.78] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ADAMTS4 antibody is generated from a mouse immunized with a recombinant protein from the human region of human ADAMTS4. Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. |
Immunogen | n/a |
Other Names | [A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM-TS 4; ADAM-TS4; ADAMTS-4; 3.4.24.82; ADMP-1; Aggrecanase-1; ADAMTS4; KIAA0688] |
Gene, Accession # | [ADAMTS4], Gene ID: 9507, NCBI: NP_005090.3, UniProt: O75173 |
Catalog # | MBS9231328 |
Price | $165, $370 |
Order / More Info | ADAMTS4 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tortorella M.D.,et al.Science 284:1664-1666(1999). Wainwright S.D.,et al.Matrix Biol. 25:317-320(2006). Sawaji Y.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. Ishikawa K.,et al.DNA Res. 5:169-176(1998). Clark H.F.,et al.Genome Res. 13:2265-2270(2003). |