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Antigenic Specificity | beta-Arrestin 1 |
Clone | [1H4-F5-C11] |
Host Species | Mouse |
Reactive Species | mouse, rat, human |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals.Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors.Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been |
Immunogen | Immunogen: Purified recombinant human beta Arrestin 1 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of beta Arrestin 1 and does not cross-react with related proteins. Sequence Similarities: Belongs to the arrestin family. |
Other Names | [ARB 1; ARB 1; ARB1; ARB1; ARR 1; ARR 1; ARR1; ARR1; ARRB 1; ARRB1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1], [ARB1; ARR1.] |
Gene, Accession # | [ARRB1], Gene ID: 408, NCBI: NP_004032.2, UniProt: P49407 |
Catalog # | MBS475001 |
Price | $335 |
Order / More Info | beta-Arrestin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |