SFPQ (C-term), 676-705 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SFPQ (C-term), 676-705 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SFPQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 676-705 amino acids from the C-terminal region of human SFPQ. DNA-and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. The SFPQ-NONO heteromer a |
| Immunogen | n/a |
| Other Names | [Splicing factor; proline- and glutamine-rich; 100 kDa DNA-pairing protein; hPOMp100; DNA-binding p52/p100 complex; 100 kDa subunit; Polypyrimidine tract-binding protein-associated-splicing factor; PSF; PTB-associated-splicing factor; SFPQ; PSF] |
| Gene, Accession # | [SFPQ], Gene ID: 6421, NCBI: NP_005057.1, UniProt: P23246 |
| Catalog # | MBS9207990 |
| Price | $165, $370 |
| Order / More Info | SFPQ (C-term), 676-705 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Heyd, F., et al. Mol. Cell 40(1):126-137(2010) Marko, M., et al. Exp. Cell Res. 316(3):390-400(2010) David, A., et al. Eur. J. Endocrinol. 162(1):37-42(2010) Olsen, J.V., et al. Cell 127(3):635-648(2006) Ong, S.E., et al. Nat. Methods 1(2):119-126(2004) |
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MYBIOSOURCE INC.
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